Table 1.
Entry | Substrate | Product | Yield[b] | dr[c] |
---|---|---|---|---|
1 | 81% | 1.7:1 | ||
2 | 81% | 2.6:1 | ||
3 | 71% | >30:1 | ||
4 | 86% | >30:1 | ||
5 | 86% | 7.6:1 | ||
6 | 85% | >15:1 | ||
7 | 84% | 16:1 | ||
8 | 77% | >30:1 | ||
9 | 56% | 2.9:1 |
See the Supporting Information for experimental procedures and spectral data.
Combined yield of the diastereomeric mixture.
Determined by 1H NMR analysis of the crude product mixture.