Skip to main content
. Author manuscript; available in PMC: 2018 Aug 28.
Published in final edited form as: Angew Chem Int Ed Engl. 2017 Jul 28;56(36):10900–10904. doi: 10.1002/anie.201705924

Table 1.

Dehydrative cyclization scope.[a]

Entry Substrate Product Yield[b] dr[c]
1 graphic file with name nihms915636t1.jpg graphic file with name nihms915636t2.jpg 81% 1.7:1
2 graphic file with name nihms915636t3.jpg graphic file with name nihms915636t4.jpg 81% 2.6:1
3 graphic file with name nihms915636t5.jpg graphic file with name nihms915636t6.jpg 71% >30:1
4 graphic file with name nihms915636t7.jpg graphic file with name nihms915636t8.jpg 86% >30:1
5 graphic file with name nihms915636t9.jpg graphic file with name nihms915636t10.jpg 86% 7.6:1
6 graphic file with name nihms915636t11.jpg graphic file with name nihms915636t12.jpg 85% >15:1
7 graphic file with name nihms915636t13.jpg graphic file with name nihms915636t14.jpg 84% 16:1
8 graphic file with name nihms915636t15.jpg graphic file with name nihms915636t16.jpg 77% >30:1
9 graphic file with name nihms915636t17.jpg graphic file with name nihms915636t18.jpg 56% 2.9:1
[a]

See the Supporting Information for experimental procedures and spectral data.

[b]

Combined yield of the diastereomeric mixture.

[c]

Determined by 1H NMR analysis of the crude product mixture.