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. 2017 May 16;1(4):299–310. doi: 10.1002/hep4.1041

Figure 2.

Figure 2

High‐fat high‐carbohydrate diet induces infiltration of activated NKT cells and CD8+ T‐cells in the liver cortex of wild‐type mice. (A) Increased plasma concentration of IP‐10 in mice on an HFHC diet. (B,C) Increased number of infiltrating NKT cells and CD8+ T‐cells, respectively, in the livers of mice on an HFHC diet. (D) Representative image (magnification ×200 and ×400) of the presence of infiltrating CD8+ T‐cells in the liver biopsies of a NASH patient (black arrow, infiltrating CD8+ T‐cells; red arrow, steatosis). The vertical bars represent mean ± SEM. The Student t test was performed for each parameter in A‐C. ****P < 0.0001; ***P < 0.001; **P < 0.01; *P < 0.05.