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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: IEEE Trans Med Imaging. 2017 Apr 25;36(9):1966–1978. doi: 10.1109/TMI.2017.2697820

Fig. 15.

Fig. 15

Performance analysis of the presented framework: when threshold for spatial coarsening changes from 0.1% to 20% of the maximum gain in global optimum (left), and when two nodes vs. one node is split for spatial refinement (right).