Table 1.
Patient and Tumor Characteristics
| Characteristic | Total (n = 170), % |
IC+CRT (n = 85), % |
CCRT (n = 85), % |
P |
|---|---|---|---|---|
| Sex | ||||
| Male | 144 (84.7) | 72 (84.7) | 72(84.7) | 1.000 |
| Female | 26 (15.3) | 13 (15.3) | 13 (15.3) | |
| Age (years) | ||||
| <60 | 107 (62.9) | 51 (60.0) | 56 (65.9) | 0.427 |
| ≥60 | 63 (37.1) | 34 (40.0) | 29 (34.1) | |
| Smoking | ||||
| Yes | 132(77.6) | 73(85.9) | 59(69.4) | 0.010 |
| No | 38(22.4) | 12(14.1) | 26(30.6) | |
| Drinking | ||||
| Yes | 129(75.9) | 60(70.6) | 69(81.2) | 0.107 |
| No | 41(24.1) | 25(29.4) | 16(18.8) | |
| Weight loss | ||||
| <10% | 139 (84.7) | 71 (83.5) | 68 (80.0) | 0.692 |
| ≥10% | 31 (15.3) | 14 (16.5) | 17 (20.0) | |
| ECOG PS | ||||
| 0 | 28 (16.5) | 14 (16.5) | 14 (16.5) | 1.000 |
| 1-2 | 142 (83.5) | 71 (83.5) | 71 (83.5) | |
| Tumor location | ||||
| Upper third | 32(18.8) | 16 (18.8) | 16 (18.8) | 1.000 |
| Middle third | 126 (74.1) | 63 (74.1) | 63 (74.1) | |
| Lower third | 12 (7.1) | 6 (7.1) | 6 (7.1) | |
| Primary tumor length | ||||
| <6 cm | 68 (40.0) | 29 (42.6) | 39 (45.9) | 0.117 |
| ≥6 cm | 102 (60.0) | 56 (65.9) | 46 (54.1) | |
| Histologic grade | ||||
| Well/Moderately differentiated | 109 (64.1) | 56(65.9) | 53 (62.4) | 0.631 |
| Poorly differentiated | 61 (35.9) | 29 (34.1) | 32 (37.6) | |
| T stage | ||||
| T1-2 | 9 (5.3) | 4 (4.7) | 5 (5.9) | 0.732 |
| T3-4 | 161 (94.7) | 81 (95.3) | 80 (94.1) | |
| N stage | ||||
| N0 | 14 (8.2) | 6 (7.1) | 8 (9.4) | 0.577 |
| N1 | 156 (91.8) | 79 (92.9) | 77 (90.6) | |
| M stage | ||||
| M0 | 28 (16.5) | 14 (16.5) | 14(16.5) | 1.000 |
| M1 | 142 (83.5) | 71 (83.5) | 71 (83.5) | |
| Pretreatment TNM stage | ||||
| III | 28 (16.5) | 14 (16.5) | 14(16.5) | 1.000 |
| IV | 142 (83.5) | 71 (83.5) | 71 (83.5) | |
| Radiotherapy technique | ||||
| IMRT | 126 (74.1) | 67 (78.8) | 59 (69.4) | 0.161 |
| 3DCRT | 44(25.9) | 18 (21.2) | 26 (30.6) | |
| Concurrent chemotherapy regimen | ||||
| Weekly | 78 (45.9) | 44 (51.8) | 34 (40.0) | 0.124 |
| Three-weekly | 92 (54.1) | 41 (48.2) | 51(60.0) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; PS, performance status.