Table 2.
Treatment-related toxicity (NCICTC 3.0)
| Event of grade ≥3 | IC+CRT (n = 85), % |
CCRT (n =85), % |
P |
|---|---|---|---|
| Hematological toxicity | |||
| Anemia | 1 (1.2) | 2 (2.4) | 1.000 |
| Leukopenia | 33 (38.8) | 21 (24.7) | 0.048 |
| Neutropenia | 28 (32.9) | 20 (23.5) | 0.173 |
| Thrombocytopenia | 8 (9.4) | 5 (5.9) | 0.387 |
| Non-hematological toxicity | |||
| Nausea/vomiting | 8 (9.4) | 5 (5.9) | 0.387 |
| Diarrhea | 2 (2.4) | 2 (2.4) | 1.000 |
| Esophagitis | 6 (7.1) | 5 (5.9) | 0.755 |
| Pneumonitis | 3 (3.5) | 2 (2.4) | 0.650 |
| Skin toxicity | 13 (15.3) | 16 (18.8) | 0.541 |
| Weight loss | 7 (8.2) | 8 (9.4) | 0.787 |
| Fatigue | 17 (20.0) | 13 (15.3) | 0.421 |
Abbreviations: NCICTC3.0: National Cancer Institute Common Toxicity Criteria (version 3.0)