Table 2.
Univariate Cox regression analysis of clinicopathological predictors of disease-free survival
| HR (95% CI) | p Value | |
|---|---|---|
| Age at surgery (continuous) | 1.00 (0.96-1.04) | 0.984 |
| Gender | ||
| Female | 1.0 (referent) | |
| Male | 1.85 (0.60-5.67) | 0.282 |
| Surgical type | ||
| Partial | 1.0 (referent) | |
| Radical | 2.03 (0.44-9.34) | 0.365 |
| Surgical methods | ||
| Open | 1.0 (referent) | |
| Minimally invasive surgery | 0.45 (0.09-2.16) | 0.319 |
| Tumor size (continuous) | 1.17 (1.07-1.28) | 0.001 |
| Symptoms at presentation | ||
| NO | 1.0 (referent) | |
| YES | 1.94 (0.65-5.80) | 0.234 |
| 2010 AJCC TNM stage | ||
| I+II | 1.0 (referent) | |
| III+IV | 8.03 (2.37-27.22) | 0.001 |
| Grade | <0.001 | |
| 1 | 1.0 (referent) | |
| 2 | 2.56 (0.57-11.46) | 0.219 |
| 3 | 14.26 (3.50-58.16) | <0.001 |
| Coagulative tumor necrosis | ||
| NO | 1.0 (referent) | |
| YES | 2.45 (0.54-11.13) | 0.247 |
| Sarcomatoid differentiation | ||
| NO | 1.0 (referent) | |
| YES | 9.24 (3.04-28.08) | <0.001 |
| Tumor thrombus | ||
| NO | 1.0 (referent) | |
| YES | 5.74 (0.69-47.55) | 0.105 |
| Microvascular invasion | ||
| NO | 1.0 (referent) | |
| YES | 2.44 (0.53-11.36) | 0.254 |
| Capsular invasion | ||
| NO | 1.0 (referent) | |
| YES | 1.40 (0.47-4.21) | 0.550 |
| Perirenal fat invasion | ||
| NO | 1.0 (referent) | |
| YES | 3.95 (0.86-18.15) | 0.077 |
| Sinus fat invasion | ||
| NO | 1.0 (referent) | |
| YES | 4.35 (0.94-20.09) | 0.060 |
| Urinary collecting system invasion | ||
| NO | 1.0 (referent) | |
| YES | 6.80 (2.01-23.00) | 0.002 |
HR, hazard ratio; CI, confidence interval; AJCC, American Joint Committee on Cancer.