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Restoration of KLF4 inhibited migration, invasion. (A) Expression of KLF4 was significantly restored by stable transfection of pcDNA3.1-KLF4 vector at both protein and mRNA levels, compared with untreated parental group and mock plasmid group. Migration and invasion (B, C) of tumor cells were determined as described in Materials and Methods section. The untreated cells were given arbitrary migration and invasiveness percentages of 100%. *p<0.05.
