Table 2.
Prognostic Factors Associated with OS in the Propensity Score-matched Cohort
| Variable | No. of cases | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| HR (95% confidence interval) | P value | HR (95% confidence interval) | P value | |||
| Age (y) (<70/≥70) | 164/42 | 1.485 (0.932-2.354) | .091 | |||
| Sex (M/F) | 192/14 | 0.959 (0.559-1.646) | .880 | |||
| HBsAg (positive/negative) | 178/28 | 1.358 (0.957-1.928) | .087 | |||
| Tumor number (1/>1) | 146/60 | 1.282 (0.981-1.676) | .069 | |||
| Tumor size (≤5/>5 cm) | 157/49 | 1.375 (1.007-1.878) | .045 | 1.321 (0.894-1.953) | .163 | |
| Milan criteria (In/Out) | 134/72 | 1.809 (1.407-2.325) | < .001 | 2.093 (1.526-2.869) | < .001 | |
| Child-Pugh A/B | 201/5 | 1.135 (0.601-2.150) | .881 | |||
| AFP (ng/mL) (<20/≥20) | 98/108 | 1.002 (0.769-1.304) | .990 | |||
| Treatment group (SR/TACE-RFA) | 103/103 | 1.182 (0.820-1.683) | .379 | |||
| PLT (109 /L) (<100/≥100) | 67/139 | 0.779 (0.586-1.037) | .087 | |||
| Institution (SYSUCC/TAHSYSU) | 143/63 | 1.347 (0.821-2.174) | .228 | |||
HR, hazard ratio; AFP, alpha-fetoprotein; PLT, Platelets; SR, surgical resection; TACE, transarterial chemoembolization; RFA, radiofrequency ablation; SYSUCC, Sun Yat-sen university cancer center; TAHSYSU, the third affiliated hospital of Sun Yat-sen university.