Table 3.
Diagnostic values of HA, circulating CD14+CD204+ M2-like monocytes, CEA, CA15-3, and their combination for breast cancer
| Markers | AUC | 95% CI | Sensitivity | |||
|---|---|---|---|---|---|---|
| 90% specificity | 95% CI | 80% specificity | 95% CI | |||
| HA | 0.798 | 0.733-0.863 | 54.3% | 0.429-0.654 | 60.5% | 0.490-0.863 |
| CD14+CD204+ | 0.861 | 0.806-0.917 | 71.6% | 0.605-0.811 | 76.5% | 0.658-0.853 |
| CEA | 0.598 | 0.513-0.682 | 14.8% | 0.079-0.245 | 33.3% | 0.232-0.447 |
| CA15-3 | 0.631 | 0.548-0.714 | 27.2% | 0.179-0.382 | 39.5% | 0.288-0.510 |
| CD14+CD204+ + HA | 0.899 | 0.853-0.946 | 74.1% | 0.631-0.832 | 84.0% | 0.741-0.912 |
| CEA + CA15-3 | 0.639 | 0.557-0.722 | 24.7% | 0.158-0.355 | 32.1% | 0.222-0.434 |
| Combination of all | 0.908 | 0.863-0.954 | 81.5% | 0.713-0.893 | 86.4% | 0.770-0.930 |