Table 2.
Gender | Female | 5 (33.3%) |
Male | 10 (66.7%) | |
Age at diagnosis | (years) | 52.45 (29.52–72.13) |
Stage | I | 3 (20%) |
II | 1 (6.7%) | |
III | 11 (73.3%) | |
IV | 0 | |
Localization | Right | 7 (46.7%) |
Left | 8 (53.3%) | |
Hormonal Activity | No | 11 (73.3%) |
Yes | 4 (26.7%) | |
• Cortisole | 1 (6.7%) | |
• Cortisole + DHEAS | 3 (20%) | |
Surgery | Open | 12 (80%) |
Laparoscopic | 3 (20%) | |
Adrenal/En bloc | Adrenalectomy | 6 (40%) |
En bloc | 9 (60%) | |
Resection | Rx | 2 (13.3%) |
R0 | 7 (46.7%) | |
R1 | 4 (26.7%) | |
R2 | 2 (13.3%) | |
Mitotic Activity | High | 4 (26.7%) |
Low | 1 (6.7%) | |
Necrosis | Yes | 9 (60%) |
No | 6 (40%) | |
Ki67 | High | 7 (77.8%) |
Low | 2 (22.2%) | |
Treatment | None | 7 (46.7%) |
Mitotan | 3 (20%) | |
Mitotane+RT | 2 (13.3%) | |
Mitotane+Systemic CT | 2 (13.3%) | |
RT+Systemic CT | 1 (6.7%) | |
Ketoconazole | 2 (13.3%) | |
Recurrence and Metastasis | Development of recurrence | 7 (46.7%) |
Recurrent operation | 3 (20%) | |
Time to recurrence | 8 (2–24) mos | |
Development of metastasis | 6 (40%) | |
Metastasectomy | 2 (13.3%) |
DHEAS: dehydroepiandrosteron sulphate; RT: radiotherapy; CT: chemotherapy