Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Histopathology analysis of rat liver tissues used for proteomic analysis
| Hours after dosing (h) | APAP dose (mg/kg) | Degeneration (centrilobular) | Necrosis (centrilobular) | ALT and AST |
|---|---|---|---|---|
| 6 | 0 | 0/4 | 0/4 | Low |
| 100 | 2/4 (minimal) | 0/4 | Low | |
| 1250 | 3/4 (minimal) | 0/4 | Low | |
| 24 | 0 | 0/4 | 0/4 | Low |
| 100 | 0/4 | 0/4 | Low | |
| 1250 | 2/4 (minimal) | 1/4 (minimal) 1/4 (mild) |
Low | |
| 1250 | 1/2 (moderate) | 2/2 (moderate) | High |
Data in the table are presented as no. of affected rats/no. of examined rats (severity of affected animals).
