Table 1.
Final Diagnosis* | Pairwise p-values† | ||||||
---|---|---|---|---|---|---|---|
Variable | ICAD (N=180) | RCVS (N=128) | IVas (N=94) | ICAD vs. RCVS | ICAD vs. IVas | RCVS vs. IVas | |
Luminal imaging findings | |||||||
Pattern of involvement‡ | Concentric, n (%) | 51 (28.8) | 59 (46.8) | 45 (48.9) | 0.002 | 0.006 | 0.81 |
Eccentric | 126 (71.2) | 67 (53.2) | 47 (51.1) | ||||
IVWI findings | |||||||
Pattern of involvement | Concentric | 16 (8.9) | 103 (80.5) | 72 (76.6) | <0.001 | <0.001 | 0.65 |
Eccentric | 164 (91.1) | 25 (19.5) | 22 (23.4) | ||||
Wall enhancement | Present | 173 (96.1) | 59 (46.1) | 89 (94.7) | <0.001 | 0.66 | <0.001 |
Absent | 7 (3.9) | 69 (53.9) | 5 (5.3) | ||||
Pattern of enhancement|| | Focal | 17 (9.8) | 0 (0.0) | 0 (0.0) | 0.010 | <0.001 | 0.065 |
Diffuse | 76 (43.9) | 42 (71.2) | 77 (86.5) | ||||
Heterogeneous | 80 (46.2) | 17 (28.8) | 12 (13.5) |
ICAD = intracranial atherosclerotic disease; IVas = inflammatory vasculopathy; IVWI = intracranial vessel wall MRI; RCVS = reversible cerebral vasoconstrictive syndrome; IVWI
Values are no. (%); observations are reads (201 lesions × 2 raters = 402 total);
Test for difference in findings between the given pair of vasculopathy groups;
Excluding 7 lesions where one rater did not determine eccentricity.