Table 3.
Rater* | Agreement | ||||||
---|---|---|---|---|---|---|---|
Variable | R1 | R2 | P-value† | % Agree‡ | Cohen’s κ | (95% CI) | |
Luminal Imaging | |||||||
Pattern of involvement§ | Concentric | 108 (55.7) | 45 (23.2) | <0.001 | 47.9% | 0.02 | (−0.07–0.11) |
Eccentric | 86 (44.3) | 149 (76.8) | |||||
Diagnosis | ICAD | 69 (34.3) | 152 (75.6) | <0.001 | 35.3% | 0.04 | (−0.03–0.12) |
RCVS | 13 (6.5) | 5 (2.5) | |||||
IVas | 25 (12.4) | 22 (10.9) | |||||
Uncertain/equivocal | 94 (46.8) | 22 (10.9) | |||||
Vessel Wall Imaging | |||||||
Diagnosis | ICAD | 81 (40.3) | 93 (46.3) | 0.003 | 81.6% | 0.72 | (0.64–0.80) |
RCVS | 55 (27.4) | 65 (32.3) | |||||
IVas | 62 (30.8) | 43 (21.4) | |||||
Uncertain/equivocal | 3 (1.5) | 0 (0.0) |
ICAD = intracranial atherosclerotic disease; LI = luminal imaging; RCVS = reversible cerebral vasoconstrictive syndrome; IVas = inflammatory vasculopathy; IVWI = vessel wall imaging;
Values are no. (%);
Test for average difference between raters;
Percent of lesions where raters gave the same classification;
Excluding 7 lesions where one rater did not determine eccentricity.