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. 2017 May 30;12(8):637–652. doi: 10.1080/15592294.2017.1334025

Table 2.

Top 10 most significant genes regulated by CORT in blood and hippocampus.

Location of Blood DMRs Gene Distance from Gene N of CpGs DMR Width areaStat Vehicle (%) CORT (%)
Chr17: 28,898,895-28,899,766 4930539E08Rik in_gene 28 872 205.1 43.3 76.7
Chr10: 17,725,094-17,727,734 Cited2 1,867 32 2,641 182.6 76.1 29.9
Chr8: 121,570,435-121,571,212 Fbxo31 in_gene 34 778 165.6 69 21.6
Chr11: 117,116,679-117,117,586 Sec14l1 in_gene 28 908 162.6 92.3 51.2
Chr7: 29,212,131-29,212,609 Catsperg1 in_gene 23 479 162.6 79.3 36.8
Chr7: 15,963,944-15,964,287 Ehd2 in_gene 23 344 161.5 35.6 71.2
Chr14: 33,189,451-33,190,294 Arhgap22 27,371 29 844 151 31.7 86.3
Chr13: 103,592,675-103,593,009 Srek1 148,939 33 335 150.1 56.5 89.8
Chr15: 82,166,760-82,168,036 Srebf2 in_gene 30 1,277 146.1 45.1 70.6
Chr15: 85,231,797-85,232,719
Fbln1
in_gene
26
923
141.6
84.3
42.9
Location of Hippocampal DMRs
Gene
Distance from Gene
N of CpGs
DMR Width
areaStat
Vehicle (%)
CORT (%)
Chr5: 75,834,926-75,835,856 Kdr 98,343 32 931 111.1 34.2 23.6
Chr12: 12,936,763-12,937,453 Mycn in_gene 30 691 86.2 47.8 35.9
Chr8: 20,281,184-20,281,505 6820431F20Rik in_gene 26 322 81.1 59.6 47.4
Chr8: 8,621,164-8,622,036 Efnb2 in_gene 19 873 80.4 56.3 37.9
Chr11: 120,280,582-120,280,938 Bahcc1 in_gene 25 357 77.3 38.1 21.5
Chr13: 74,533,968-74,534,503 Zfp825 53,912 20 536 76 41.8 30.1
Chr4: 141,477,474-141,477,726 Spen in_gene 16 253 72.3 39.1 19.8
Chr8: 20,596,693-20,597,331 Gm21119 18,233 19 639 64 55.8 42.9
Chr7: 13,006,038-13,006,361 Zbtb45 in_gene 14 324 60.8 61.8 40.3
Chr7: 45,465,579-45,466,110 Bax in_gene 16 532 59.6 54.9 42.5