Table 2.

Regression of M-value on neighborhood socioeconomic disadvantage in stress pathway genes (n = 1,226).

	AVP		CRF		SCL6A4
	β (SE)	P-value	β (SE)	P-value	β (SE)	P-value
Neighborhood Socioeconomic Disadvantage	−0.004 (0.004)	0.220	−0.001 (0.003)	0.752	0.001 (0.004)	0.795
Promoter	1.251 (0.003)	<2.0E-16	3.147 (0.012)	<2.0E-16	−3.255 (0.004)	<2.0E-16
Shore/Shelf	3.067 (0.007)	<2.0E-16	2.010 (0.009)	<2.0E-16	1.292 (0.004)	<2.0E-16
Neighborhood Socioeconomic Disadvantage * Promoter	−0.005 (0.003)	0.073	−0.031 (0.013)	0.014	−0.006 (0.004)	0.171
Neighborhood Socioeconomic Disadvantage * Shore/Shelf	0.020 (0.007)	0.004	0.021 (0.009)	0.015	0.017 (0.005)	0.0003

Regression models control for age, sex, race/ethnicity, childhood SES, adult SES, and enrichment scores for each of 4 major blood cell types (neutrophils, B cells, T cells, and natural killer cells). Higher values indicate more neighborhood socioeconomic disadvantage. Asterisks (*) indicate interaction terms.