Table 1.
Material | dn (nm) | PI | ζ (mV) | EE% | DL% |
---|---|---|---|---|---|
NLC | 27.9±1.7 | 0.28±0.01 | −17.9±0.6 | – | – |
NLC/A-317491 | 36.5±4.3 | 0.27±0.01 | −12.8±1.0 | 75.5±4.94 | 7.02±0.43 |
CSOSA/NLC | 41.2±3.0 | 0.34±0.01 | 27.0±0.9 | – | – |
CSOSA/NLC/A-317491 | 48.1±5.2 | 0.22±0.02 | 28.3±0.4 | 64.4±2.57 | 2.10±0.08 |
Note: Data presented as mean ± standard deviation.
Abbreviations: CSOSA, chitosan oligosaccharide-g-stearic acid; DL%, drug loading; EE%, entrapment efficiency; NLC, nanostructured lipid carrier; PI, polydispersity index.