Table 3.

Comparison of AUROC, sensitivity and specificity for the MLA applied to severe sepsis detection and SIRS criteria, MEWS, the SOFA score and the qSOFA score on patient physiological data collected during the study

	MLA	SIRS	MEWS	SOFA	qSOFA
AUROC	0.952 (0.946 to 0.958)	0.681	0.524	0.756	0.518
Sensitivity	0.900 (0.870 to 0.930)	0.590	0.365	0.910	0.288
Specificity	0.900 (0.878 to 0.922)	0.764	0.667	0.181	0.750

A 95% CI for the MLA is also included in parentheses.

AUROC, area under the receiver operator characteristic curve; MEWS, Modified Early Warning Score; MLA, machine learning algorithm; SIRS, Systemic Inflammatory Response Syndrome; qSOFA, quick Sequential Organ Failure Assessment.