Skip to main content
. 2017 Aug 3;8(51):88537–88551. doi: 10.18632/oncotarget.19877

Figure 5. Adiponectin negatively regulates the MEK-ERK-p90RSK axis.

Figure 5

(A) Cells were incubated with 10 ng/ml EGF for 1 h followed by adiponectin (APN) or PBS (Con) treatment for 2 h. Then, the cellular extracts were analyzed for expression of the indicated proteins. (B, C, D) Quantification for phosphorylation of MEK, ERK and p90RSK. The results are expressed as the mean±s.d. of three independent experiments (one-way analysis of variance followed by Bonferroni post-tests; *p<0.05, **p<0.01, ***p<0.001). (E) Cells were treated at the indicated conditions for 2 h followed by Immunoblotting for phosphor-p90RSK. This experiment was performed twice with similar results.