Figure 5. Administration of TA inhibits development of peritoneal fibrosis in a murine model of peritoneal fibrosis induced by high glucose dialysate.
Peritoneal membrane was collected at 28 days after PDF injection with or without administration of TA (70 mg/kg, daily). (A) Photomicrographs illustrate Masson trichrome staining of the peritoneum. (B) The graph shows the thickness of the compact zone measured from ten random fields (original magnification, ×200) of six mice peritoneal samples. (C) The graph shows the score of the Masson-positive submesothelial area (blue) from ten random fields (original magnification, ×200) of six mice peritoneal samples. Data are represented as the means±SD (n=6). Means with different letters (a-c) are significantly different from one another (P<0.05).