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. 2017 Oct 4;8(51):88845–88856. doi: 10.18632/oncotarget.21483

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Copyright: © 2017 Bach et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Pearson correlation between the total number of EVs (as determined by high-resolution flow cytometry) in the sucrose fractions of the porcine notochordal cell-conditioned medium (NCCM) extracellular vesicle (EV) pellets after size exclusion chromatography (SEC) and 100,000g ultracentrifugation (UC) and the GAG (a) and GAG/DNA (b) content of canine CLC micro-aggregates treated with a serial dilution of EV_UC (NCCM-derived EVs obtained after SEC and subsequent 100,000g UC). n = 6 porcine NCCM donors tested on a pool of 4 canine CLC donors. **,***: significant correlation (p<0.01, p<0.001, respectively). GAG: glycosaminoglycan.