Figure 3. miR-216a suppresses liver metastasis of GC cells in mice.

MGC-803 cells that were transfected with precursor miR-216a (pre-miR-216a) or scrambled controls (miR-control) were intravenously injected into tail vein in nude mice. HE staining revealed that miR-216a overexpression significantly reduced the number of metastatic nodes of MGC-803 cells in nude mice livers. Scale bar: 1mm. n = 6, ^*P<0.05 by t test.