Table 2. Multivariate Cox regression analysis of 5-year overall survival of gastric cancer patients (n=90).

Variables	Overall survival
	HR	95% CI	P
Lymph node metastasis (present vs absent)	4.14	2.48-5.05	0.035*
Tumor size (cm, >5 vs ≤5)	1.46	0.92-1.88	0.091
Venous infiltration (present vs absent)	1.20	0.80-1.79	0.166
Invasive depth (T2-T4 vs T1)	2.05	1.41-2.60	0.007*
Tumor differentiation (poor/signet vs well/moderate poor)	1.37	0.82-1.86	0.364
TNM stage (III+IV vs I+II)	3.23	2.41-4.23	0.006*
miR-216a expression (low vs high)	2.12	1.51-2.50	0.018*

HR, hazard ratio; CI, confidence interval. ^*Statistically significant.