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. 2017 Oct 4;8(51):88988–89004. doi: 10.18632/oncotarget.21640

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Copyright: © 2017 Huang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) It was indicated by immunofluorescence that CK2α and SphK1 showed visible cytoplasmic co-localization in GMCs, which strengthened apparently after 30 min of HG treatment. (B and C) Co-immunoprecipitation and reverse co-immunoprecipitation assay were applied to detect the interaction between CK2α with SphK1. This interaction reached a peak at 30 min after HG treatment.