Table 3. Top 10 driver gene per subtype attained by DriverNet [5].
C1 | C2 | C3 | C4 | C5 |
---|---|---|---|---|
TP53 | TP53 | TP53 | TP53 | TP53 |
CSNK2A1 | MYC | MYC | PIK3CA | ERBB2 |
EP300 | CCND1 | CDKN2A | MYC | MYC |
PRKCA | PAK1 | RB1 | IGF1R | PIK3R1 |
UBQLN4 | CSNK2A1 | STAT5A | MAP2K4 | SMAD3 |
SHC1 | ERBB2 | MCL1 | LRP2 | ACTL6A |
MYC | IGF1R | IGF1R | GATA3 | TTN |
CCDC85B | MAPT | TUBG1 | MCL1 | U2AF2 |
RELA | RELA | IKBKB | CDH1 | SMAD2 |
PAK1 | PIK3R1 | BRCA1 | TTN | CDKN2A |