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. 2017 Oct 6;8(51):89040–89054. doi: 10.18632/oncotarget.21648

Table 4. Subgroup analyses stratified by TNM stage for all EOC patients (OS).

Stage I Stage II Stage III Stage IV
Marital status
 Married Ref. Ref. Ref. Ref.
 Divorced/separated 1.56(1.12, 2.18) a 1.07(0.75, 1.54) 1.21(1.08, 1.37)a 1.13(1.00, 1.28)
 Widowed 1.52(1.11, 2.08)a 1.38(1.01, 1.87)b 1.13(1.01, 1.27)b 1.07(0.96, 1.20)
 Never married 1.19(0.91, 1.57) 1.54(1.15, 2.06)a 1.04(0.93, 1.16) 1.11(0.99, 1.25)
Age
 <60 Ref. Ref. Ref. Ref.
 60-69 1.06(0.79, 1.43) 1.05(0.78, 1.43) 1.21(1.09, 1.33)a 1.12(1.00, 1.24)b
 70-79 2.37(1.75, 3.22)a 2.10(1.53, 2.88)a 1.59(1.43, 1.78)a 1.19(1.06, 1.34)a
 ≥80 5.03(3.56, 7.10)a 3.54(2.51, 4.99)a 2.12(1.84, 2.43)a 1.62(1.41, 1.86)a
Race
 White Ref. Ref. Ref. Ref.
 Black 1.26(0.88, 1.80) 1.43(0.97, 2.09) 1.20(1.04, 1.38)b 1.07(0.94, 1.22)
 Others 0.78(0.56, 1.10) 0.84(0.56, 1.25) 0.99(0.86, 1.13) 1.03(0.89, 1.18)
Diagnosis year
 2004-2008 Ref. Ref. Ref. Ref.
 2009-2012 0.88(0.69, 1.11) 1.02(0.81, 1.30) 0.92(0.85, 1.00) 0.96(0.88, 1.04)
Grade
 I Ref. Ref. Ref. Ref.
 II 1.46(1.00, 2.13) 1.17(0.66, 2.08) 1.51(1.08, 2.11)b 1.38(0.87, 2.17)
 III 1.74(1.18, 2.55)a 1.60(0.92, 2.77) 1.90(1.39, 2.62)a 1.32(0.86, 2.02)
 IV 1.56(0.98, 2.48) 1.22(0.67, 2.21) 1.76(1.28, 2.44)a 1.26(0.81, 1.95)
 Unknown 1.66(1.12, 2.46)b 1.66(0.93, 2.97) 1.84(1.33, 2.55)a 1.21(0.79, 1.86)
Histological type
 Serous Ref. Ref. Ref. Ref.
 Mucinous 0.94(0.66, 1.34) 1.05(0.60, 1.84) 2.50(1.94, 3.22)a 2.10(1.62, 2.72)a
 Clear-cell 1.09(0.81, 1.48) 1.16(0.77, 1.76) 1.59(1.31, 1.94)a 1.55(1.20, 2.00)a
 Endometrioid 0.56(0.40, 0.78)a 0.68(0.47, 0.98)b 0.50(0.39, 0.64)a 0.95(0.72, 1.26)
 Others 0.76(0.56, 1.04) 1.21(0.93, 1.58) 1.09(0.99, 1.21) 1.13(1.03, 1.24)b
Surgery
 Yes Ref. Ref. Ref. Ref.
 No 0.17(0.11, 0.25)a 0.22(0.15, 0.34)a 0.34(0.30, 0.40)a 0.40(0.36, 0.45)a

a: p<0.01; b: p <0.05.