Table 2. Patients’ clinicopathological characteristics at time of early or late locoregional recurrence.

	ELR(<12m) (N=30)	LLR(≥12m) (N=44)	P
Age
<65	22(43.1%)	29(56.9%)
≥65	8(34.8%)	15(65.2%)	0.498
Gender
Male	20(38.5%)	32(61.5%)
Female	10(45.5%)	12(54.5%)	0.575
Diameter of recurrent lesion
<2	15(46.9%)	17(53.1%)
≥2	15(35.7%)	27(64.3%)	0.333
Site of recurrence
Anastomotic recurrence	5(26.3%)	14(73.7%)
Local lymph node recurrence	25(45.5%)	30(54.55)	0.143
Response
CR+PR	4(19.0%)	17(81.0%)
SD+PD	26(49.1%)	27(50.9%)	0.018
Serum CA 72-4
≤6.9U/mL	17(32.1%)	36(67.9%)
>6.9U/mL)	8(57.1%)	6(42.9%)	0.085
Serum AFP
≤10ng/ml	24(37.5%)	40(62.5%)
>10ng/ml	4(80.0%)	1(20.0%)	0.150
Serum CEA
≤5ng/ml	17(34.7%)	32(65.3%)
>5ng/ml	13(52.0%)	12(48.0%)	0.211
Serum CA199
≤37U/mL	24(45.3%)	29(54.7%)
>37U/mL	6(28.6%)	15(71.4%)	0.187