Table 1. Classification of histone acetyltransferases and deacetylases.
Members | Location | |
---|---|---|
HATs | ||
Type A | GNAT, p300/CBP, MYST, basal TF, and NRCF | Nucleus |
Type B | HAT1, HAT2, HatB3.1, Rtt109, and HAT4 | Cytoplasm |
HDACs | ||
Class I | HDAC1, HDAC2, HDAC3, HDAC8 | Nucleus |
Class II | II a: HDAC4, HDAC5, HDAC7, HDAC9 | Nucleus/cytoplasm |
II b: HDAC6, HDAC10 | Mainly cytoplasm | |
Cass III | SIRT1-7 | Nucleus/cytoplasm |
Class IV | HDAC11 | Nucleus/cytoplasm |