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. 2017 Nov 15;12(11):e0187363. doi: 10.1371/journal.pone.0187363

Table 4. Characteristics and results of studies examining effects of more than one music therapy/music-based intervention session on patients with substance use disorders.

Study Outcome EG CG Type of intervention Frequency/ duration Measurement tools Population Results
Albornoz[39] Depression (self-rating/ therapist rating) N = 12
Whole sample:
N = 24 m
Age: 16–60
Addiction and depression problem
N = 12 MT
improvisation
(independent therapy)
12 sessions, 2h per week, 3 months BDI
Hamilton Rating Scale for Depression
Males
Inpatient treatment for substance abuse
Venezuela
• Lower post- than pre-test scores for self-rated depression for EG ** and CG *, d = 0.51 across both groups (Power for comparison: 34%)
• Lower post- than pre-test scores for therapist-rated depression for EG ** and CG *, d = 0.90 across both groups (Power for comparison: 78%)
• Lower post-test scores for therapist-rated depression for EG compared to CG *, but not for self-rated depression
Cevasco
et al.[43]
Anxiety
Anger
Depression
Stress
N = 20 fm
Age: 19–42
- MT
competitive games, dancing or rhythm activities
12 sessions, 1h, twice a week
each therapy 4 sessions
State-Trait Anxiety Inventory (STAI)
Novaco Anger Inventory Short Form (NAI)
10-point Likert scales
Females
Outpatient substance abuse program
USA
• No overall effects of MT methods, individual effects of MT methods
• Average daily percentage of decrease a: Indicated progress for several individuals on decreased levels of depression, stress, anxiety, and anger
• Mortality rate: 50%; remaining clients with lower anxiety ** and anger *** values
Dickerson
et al.[48]
Treatment retention and completion Substance use
Problem severity
Comfort and strength derived from spirituality
Well-being
Cognitive functioning
Cultural identity
Adoption of principles
Physical and psychiatric symptoms
N = 10
(50% m)
Age: 19–71
(M = 52.5)
- MBI
(drumming teacher and counselor)
Drum-assisted recovery therapy for Native Americans (DARTNA)
(independent therapy)
24 sessions, 3h, twice a week Substance Use Report
Addiction Severity Index, Native American Version (ASI-NAV)
Functional Assessment of Chronic Illness Therapy (FACIT): Spiritual Questions Only Expanded, Fatigue (FACIT-F)
Functional Assessment of Cancer Therapy–Cognitive Functions (FACT-Cog)
American Indian/ Alaska Native Cultural Identity Scale
General Alcoholics Anonymous Tools of Recovery (GAATOR 2.1)
BSI
Outpatient setting
Native Americans
USA
• 50% treatment completion (80% until week 6)
• Improved psychiatry status * after 6 weeks, improved medical status* after 12 weeks (ASI-NAV)
• Spirituality: Improved meaning/peace ** and total score ** after 12 weeks (FACIT)
• Improved physical and functional well-being after 12 weeks * (FACIT-F)
• No improvements in adoption of principles, physical and psychiatric symptoms or cognitive functions (GAATOR 2.1, BSI, FACT-Cog)
Dougherty[50] Attendance Age: adolescent-geriatric
100% alcohol
- MT
music listening (structured sessions)
sing along (group)
structured sessions: 3–4 weeks, once a week
sing along: 30 min, biweekly
Percent of attendance at any given time Inpatient rehabilitation/ Therapeutic community for alcohol dependency
USA
• 80–90% attendance
Gallagher & Steele[49] Mood
Participation
On-task behavior
N = 188
Age: 20–59
(M = 36)
Dually diagnosed with SUD and MI
MT
music listening, group participatory music, playing instruments, relaxing, lyric analysis, drumming, songwriting, music and muscle tone/pulse rate
45min, once a week Roger's (1981) Happy/ Sad Faces Assessment Tool
Therapist rating
Outpatient counseling
(9 month stay)
USA
• 91% active participation a
• 82% expression of thoughts and feelings a
• 68% positive mood changes
• 64% no mood changes during the session
• 53% not sociable a
• 46% participation in processing the session a
• 60% constricted or blunted affect after the session a
Gallant et al.[44] Client attitudes
Psychosocial functioning
N = 6 couples
Age: 31–51
(Md = 43)
Various drug addictions
- MBI (social worker)
music listening,
lyric analysis, relaxation
4 sessions, 2h, over 2 weeks 20-Item Hudson Psychosocial Screening Instrument
Content analysis
Outpatient recovery
Canada
• 5/6 patients rated MT as “very helpful“
• On average clients were less anxious, less depressed, and had fewer relationship problems.
• Average Hudson Score decreased from pre to post.* Cohen’s U3 = 88%.
• Content: Problem definition (55.8%), problem solving (44.2%), motivation-activation (38%), problem definition (36.6%), assessment (13.1%), goal setting (8.8%), action plan development (3.5%), cognition (68%), affective or emotive expression (32%)
○    “feeling” associated with music (55%) and “thinking” associated with lyrics (78%) more often.***
Howard[42] Depressiogenic thought frequency
State immediate goals
Sample A:
N = 8 fm
Age: M = 34.9
Sample B:
N = 12 adolescents
Age: 15–17
Chemical addictions
Within subjects comparison (PT vs. MT) or between samples comparison MT
lyric analysis
(PT also including lyric analysis)
6 sessions (alternating music and poetry), 45min, 6 weeks Automatic Thoughts Questionnaire (ATQ)
Goal attainment form (GAF)
2 inpatient substance abuse treatment facilities (rehab-ilitation center)
USA
• No differences in depressiogenic thought frequency and state immediate goals between groups or type of therapy for ATQ, GAF, or off-task behavior
• High percentage of on-task behavior a
Hwang & Oh[45] Depression
Anxiety
Anger
Stress
N = 42 mc
Age: 31–73
(M = 50.2)
100% alcohol
Between methods comparison
MT
singing, listening, playing instruments (therapist- or patient-selected activities)
12 sessions
(4 sessions each therapy)
0.5h, twice a week
10-point Likert Scales Males
Inpatient alcohol treatment program
South Korea
• High pretest scores of anxiety, anger, depression, and stress for singing a
• Decreased depression **, anxiety **, anger **, and stress ** in posttest
• No differences between methods
• No differences between patient- and therapist-selected activities at all
• Significant reduction in stress and depression for therapist-chosen activities during singing *
James[20]
Study 1
Locus of control N = 10
Whole sample:
N = 20 adolescents
(50% m)
Age: M = 15.8
Chemical addictions
Occupational therapy craft group (waitlist)
N = 10
MT
music listening
lyric analysis
4 sessions, 1h, one week Abbreviated Internal External Locus of Control Scale Adolescents
Inpatient rehabilitation service for chemical dependency
USA
• Greater pre-post increase in internal locus of control for EG than CG *
James[20]
Study 2
Locus of control N = 10
Posttest only
Whole sample:
N = 20 adolescents
(55% m)
Age: M = 16.4
Chemical addictions
Occupational therapy craft group (waitlist)
Pretest only
N = 10
MT
music listening
lyric analysis
4 sessions, 1h, one week Abbreviated Internal External Locus of Control Scale Adolescents
Inpatient rehabilitation service for chemical dependency
USA
• Greater internal locus of control for EG than CG *
K. M. Murphy[38] Motivation
Depression
Coping Skills
GIM + standard program
N = 9
Whole sample:
N = 16
(56.3% m)
Age: 19–55
M = 37.2
56.3% polydrug
37.5% alcohol
6.3% cannabis
Standard program
N = 7
MT
GIM
(relaxation, imagery focus, music imaging, drawing or journaling)
8 sessions, 50-60min, 21 days Importance, Confidence, Readiness Ruler (ICR)
Beck Depression Inventory (BDI)
Sense of Coherence Scale (SOC)
Inpatient residential substance abuse treatment
USA
• No differences in coping skills, depression, and motivation between EG and CG in pre- and posttest
• Depression a: CG 46% decrease, EG 75% decrease
• Retention rate a: CG 50%, EG 75%
Oklan & Henderson[40] Depression
Psychiatric symptoms
Coping skills
Case study
N = 1 m
Age: 14
- MBI (unclear)
Recorded Music Expressive Arts (RMEA) therapy with songwriting and production
(independent therapy)
16 sessions, 75min, 16 weeks BDI-II
Symptom Checklist 90-R (SC-90-R)
Adolescent Coping Orientation to Problems Experienced (A-COPE)
Adolescent
Outpatient psychological treatment, inhalant abuse, case study
USA
• Depression: Reduced SC-90-R Depression score, no reduction in BDI-II after 10 weeks (normal range) b
• Reduction in obsessive-compulsive, depressive, psychotic, anxiety, and overall symptoms c
• Increased seeking spiritual support, positive imagery, self-reliance c
• Decreased physical diversion, humor c
Ross et al.[15] Problem Severity
General functioning
Motivation
Physical and psychiatric symptoms
Medication adherence
Attitudes towards MT and therapist
MT characteristics
N = 80
(80% m)
Age: 20–57
(M = 39.7)
Dually diagnosed with MI and SUD
50% alcohol
37% cocaine
20% cannabis
19% polydrug
14% opiates
- MBI (unclear)
music and imagery (listening), drumming, improvisation
1h, one to more than 6 sessions Addiction Severity Index
Clinical Global Impression Severity Scale (CGI), Global Assessment of Function Scale (GAF)
SOCRATES
BSI
MT Questionnaire
Number of sessions
Inpatient dual diagnosis unit
USA
• Pretest variables unrelated to MT characteristics and MT Questionnaire
• 100% medication adherence a
• 71% appeared at outpatient aftercare treatment a
• Number of sessions positively associated with aftercare appointment***
Pre- vs. posttest:
• Relationship between MT appreciation and changes in CGI **
• Relationship between therapist appreciation and changes in CGI **, GAF *, and Taking Steps *
• Relationship between MT appreciation and attitudes towards the therapist ***
Cross-sectional analyses at discharge
• Relationship between MT appreciation and Taking Steps *
Relationship between therapist appreciation and Ambivalence *, Taking Steps*
Silverman[47] Perceived effectiveness and enjoyment
Intervention assessment compared to other groups
N = 8 fm
Age: 19–65
100% chemical dependency
- MT
music games, relaxation training, lyric analysis, songwriting
8 sessions, once a week 25-point analogue scales Females
Inpatient chemically dependency treatment
USA
• No differences between the interventions regarding enjoyment and effectiveness
• Mean scores for enjoyment/ effectiveness nearly at maximum a
• 50% reported MT as more effective and enjoyable than other groups a
Yun & Gallant[41] Forgiveness and grief
Depression
N = 21 fm
Age: 28–64
(M = 48)
SUD due to forgiveness/grief issues
MBI (counselor)
listening, lyric analysis
Individual setting
12 sessions per client, 1h, biweekly, 6 month Forgiveness Grief Perspectives Scale (FGPS)
BDI
Females
Outpatient rehabilitation center, Canada
• Decrease in forgiveness and grief from pre- to posttest (d = 1.95) ***
• Decrease in depression from pre- to posttest (d = 2.42) ***
• Positive correlation between forgiveness/grief and depression in pretest
(r = .54) ***, and posttest (r = .58) ***

Effect sizes are only listed when reported in the articles. For music-based intervention (MBI) studies, conducting persons are listed in brackets. BDI = Beck Depression Inventory; BSI = Brief Symptom Inventory; CG = control group; EG = experimental group; fm = female; m = male; MBI = music-based intervention; MI = Mental illness; MT = music therapy; pd = prescription drugs; SUD = substance use disorders

a Frequency counts.

b Results based on a criterion of clinical significance, i.e., changes by at least one standard deviation of the mean.

c Results based on scores from 36 participants.

*p < .05.

** p < .01.

*** p < .001