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. 2017 Nov 15;12(11):e0188043. doi: 10.1371/journal.pone.0188043

Fig 1. The effect of escitalopram (15 mg/kg) and NHT (30 mg/kg) treatments on stress-induced alterations in ethanol preference.

Fig 1

(A) A diagram depicting study design of experiment 1. After acclimation, mice were submitted to UCMS or naïve conditions (4 weeks), subsequently treated with saline, escitalopram or NHT (3 weeks) and screened for ethanol preference (6 days). (B) Stress diminished ethanol preference, while both NHT and escitalopram reversed this stress-induced diminution. n = 15–17 mice per group. #P<0.05 vs. naïve group. **P<0.01 vs. UCMS + saline group.