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. 2017 Nov 15;12(11):e0188068. doi: 10.1371/journal.pone.0188068

Table 3. Cyclin D1 expression and CCND1 amplification in breast cancer subtypes.

Subtype Cyclin D1 Negative Cyclin D1 <10% Cyclin D1 10–50% Cyclin D1 >50% CCND1 Not A CCND1 low A CCND1 high A
Luminal A 0 5 (7.3%) 22 (32.4%) 41 (60.3%) 56 (82.3%) 11 (16.2%) 1(1.5%)
Luminal B 2 (3.2%) 1 (1.6%) 15 (23.8%) 45 (71.4%) 45 (71.4%) 5 (7.9%) 13 (20.7%)
HER2 0 4 (30.8%) 5 (38.5%) 4 (30.8%) 12 (92.3%) 0 1(7.7%)
Triple Negative 10 (28.6%) 11 (31.4%) 10 (28.6%) 4 (11.4%) 32 (91.4%) 1 (2.9%) 2 (5.7%)

Not A: not amplified, low A: amplification ≤10 signals per nuclei, high A: amplification >10 signals