Table 2.

Clusters with significant CBF decrease in T2DM relative to age-matched controls

	N Voxels	Peak-t	Peak-t MNI coordinates	Anatomical Locations	% Cluster	% Region
Posterior cluster	32240	4.63	−2, −8, 24	Cerebellum
				Cerebelum_Crus1_R	4.61	56.16
				Cerebelum_Crus1_L	2.05	25.39
				Cerebelum_Crus2_R	4.63	70.48
				Cerebelum_Crus2_L	2.68	45.62
				Cerebelum_4_5_R	0.92	34.26
				Cerebelum_6_R	3.68	66.07
				Cerebelum_6_L	1.20	22.90
				Cerebelum_7b_R	1.17	70.60
				Cerebelum_7b_L	0.72	39.83
				Cerebelum_8_R	4.18	58.41
				Cerebelum_9_R	1.72	68.92
				Vermis_4_5	1.16	56.39
				Vermis_6	0.41	35.58
				Vermis_7	0.31	52.06
				Vermis_8	0.59	77.78
				Vermis_9	0.43	80.46
				Vermis_10	0.11	31.25
				Basal Ganglia
				Caudate_R	1.40	45.47
				Caudate_L	0.97	32.43
				Thalamus_R	1.44	43.80
				Thalamus_L	1.32	38.82
				Occipital Lobe
				Calcarine_R (Visual)	2.40	41.64
				Calcarine_L (Visual)	6.18	88.22
				Cuneus_R	0.93	31.00
				Cuneus_L	3.91	82.63
				Fusiform_L	1.28	17.84
				Lingual_R	4.22	59.09
				Lingual_L	3.61	55.56
				Occipital_Sup_L	2.33	54.90
				Limbic System
				Cingulum_Post_R	0.85	82.09
				Cingulum_Post_L	1.37	95.46
				Parietal Lobe
				Precuneus_R	1.59	15.71
				Precuneus_L	3.08	28.17
Anterior cluster	1068	3.78	−44, 60, −10	Frontal Lobe
				Frontal_Sup_L	17.51	5.20
				Frontal_Inf_Orb_L	1.40	0.89
				Frontal_Mid_L	4.49	0.99
				Frontal_Mid_Orb_L	12.55	15.09
				Frontal_Sup_Orb_L	2.25	2.49

%Cluster indicates the percentage of each cluster that falls within the defined region, %Region indicates the percentage of each defined region that falls within the cluster. The listed anatomical regions are either “%Cluster” > 1% or “%Region” > 30%.