Fig. 2. SA-mutant pseudoviruses are more sensitive to heparin inhibition than wild-type pseudoviruses.
Infectivity of the indicated pseudovirus was measured in the presence of a two-fold dilution series of heparin. Quadruplicate values were averaged and expressed as percent inhibition compared to untreated virus control. Panels (A–C) show results for ART cells, while panel (D) was performed using wild-type SV40 pseudovirus on the indicated cell types. Similar results were obtained for panels (A–C) using SFT cells (Supplemental Figure 3) and 293TTs (data not shown). Results are representative of four to six independent experiments. Error bars represent SEM.