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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Cell Rep. 2017 Oct 24;21(4):859–866. doi: 10.1016/j.celrep.2017.09.089

Figure 3. Aberrantly High Level of SREBP Transcriptional Activity Contributes to the Dendrite Morphogenesis Defects in easKO Mutants.

Figure 3

(A–C) Sample images showing dendrite morphology for the indicated genotypes.

(D and E) Quantification of total dendritic length (D) and number of branches (E) for neurons expressing constitutively active forms of SREBP (srebp.1-452), full-length SREBP, and RNAi construct targeting SREBP. n = 5 for ppk>srebp. n = 6 for all of the other genotypes.

(F and G) Western blot of larval brains showing the full-length (Fl-SREBP) and constitutively active, mature (m-SREBP) forms of SREBP protein in wildtype and easKO mutants. Tubulin was used as a loading control.

(H–N) Sample images showing dendrite morphology for the indicated genotypes.

(O and P) Quantification of total dendritic length (O) and number of branches (P) for the indicated genotypes. One-way ANOVA tests were used. Results of comparison between easKO mutants and each genotype are labeled on top of each column. n = 7 for wildtype and n = 6 for easKO mutants.

Scale bars represent 30 μm.