Table 3. Changes in eGFR and UACR by Urate-Lowering Agents.
| 0 week | Urate < 6.0 mg/dL | 52 weeks | |
|---|---|---|---|
| eGFR (mL/min/1.73 m2) | |||
| Allopurinol | 76.0 ± 6.8 | 80.0 ± 5.5 | 82.4 ± 9.8 |
| Benzbromarone | 74.7 ± 6.9 | 88.1 ± 10.0* | 85.0 ± 9.0* |
| Febuxostat | 60.3 ± 3.6 | 64.8 ± 3.9* | 63.1 ± 3.9 |
| UACR (mg/g Cr) | |||
| Allopurinol | 22.9 ± 9.3 | 13.5 ± 6.0 | |
| Benzbromarone | 9.7 ± 1.9 | 15.2 ± 6.4 | |
| Febuxostat | 119.3 ± 44.7 | 121.3 ± 50.8 |
*P < 0.05 vs. 0 week.