TABLE 2 .

Distribution of most frequent factor H-binding protein variant and peptide identities in the panel of 442 NmB strains

Variant	fHbp peptide IDa	Frequency (n = 442)	% of total	Predicted coverage (95% CI) by fHbp	Predicted coverage (95% CI) by all antigens
1	1b	144	33	99 (99–99)	99 (99–99)
	13	25	5.7	24 (0–76)	68 (52–92)
	4	22	5.0	100 (91–100)	100 (100–100)
	14	17	3.8	94 (47–100)	100 (94–100)
	110	8	1.8	100 (100–100)	100 (100–100)
	12	6	1.4	100 (17–100)	100 (67–100)
	Other IDs	42	9.5	81 (57–86)	100 (74–100)
Total for variant 1		264	60	89 (77–95)	97 (89–99)
2	19	48	11	0	94 (56–98)
	24	32	7.2	0	91 (41–100)
	16	22	5.0	0	82 (27–86)
	21	13	2.9	0	92 (62–100)
	25	11	2.5	9.1 (0–9.1)	55 (36–64)
3	31	7	1.6	0	86 (0–86)
	30	5	1.1	0	80 (60–100)
	76	5	1.1	0	100 (100–100)
2/3	Other IDs	35	7.9	0	66 (43–83)
Total for variants 2 and 3		178	40	0.5 (0–0.5)	83 (46–91)

^aID, identification number in PubMLST Neisseria sequence typing database. fHbp, factor H-binding protein.

^bSubvariant included in MenB-4C multicomponent vaccine.