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. 2017 Nov 15;2(6):e00497-17. doi: 10.1128/mSphere.00497-17

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Copyright © 2017 Tebbji et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — C. albicans ORF C2_03930C_A encodes the SWI/SNF fungus-specific subunit, Snf6. (A) Conserved N-terminal region of fungal Snf6. The similarity of the conserved CaSnf6 regions to ScSnf6 (S. cerevisiae), CgSnf6 (C. glabrata), and KlSnf6 (Kluyveromyces lactis) is shown. Identical residues are indicated with asterisks. Conserved and semiconserved substitutions are denoted by colons and periods, respectively. (B and C) Snf6 is a bona fide component of the SWI/SNF complex. Both tandem affinity purification–mass spectrometry (B) and coimmunoprecipitation (C) confirmed the interaction of Snf6 with the SWI/SNF complex. Ab, antibody.