Fig. 1.

Changes in resting physiological variables during the Xtreme Alps expedition. All values are presented as means ± SEM, displayed separately for Trek 1 and Trek 2 (solid and dotted lines, respectively) as Trek 1 ascended one day faster from the Gnifetti Hut (3611 m) to the Margherita Hut (4559 m) due to inclement weather conditions. Each arrow represents the administration of 3 x doses of either treatment or placebo supplement (1 dose before every meal each day), starting 3 days prior to each testing period. SL = sea level testing, D1 – D5 = altitude testing days 1–5. Panel 1A - ascent profile, 1B - resting oxygen saturation per expedition day, 1C – resting respiration rate, 1D – resting heart rate, and 1E – resting blood pressure (systolic over diastolic).