Fig. 3.
Graphs showing mean exhaled NO and breath condensate values for control (low nitrate placebo) and supplement (high nitrate intervention) groups at sea level (SL) and days 1–5 (D1 - D5) at 4559 m altitude. Where available, corresponding values for untreated laboratory staff members is also presented. Significant rises were seen in exhaled NO and breath condensate nitrite in response to dietary nitrate treatment, but not breath condensate nitrate or RxNO. A: Partial pressure of exhaled NO (PeNO) over time, B: Breath condensate nitrate concentration over time, C: Breath condensate nitrite concentration over time, D: Breath condensate nitrosation products (RxNO) concentration over time.
There were moderate correlations between Fractional exhaled NO (FeNO) and Exhaled Breath Condensate nitrite concentrations at sea level and at altitude in both the placebo (graph E) and the treatment (graph F) groups. However, this analysis is limited by low n values at sea level, particularly in the treatment group. rS - correlation coefficient of Spearman Rank test (no adjustment for repeated measures).