Table 7. Screening and diagnostic criteria for cystic fibrosis-related diabetes and interpretation of blood serum glucose results by means of the oral glucose tolerance test.
OGTT, mg/dl | Interpretation | Fasting BSG | BSG-2 h | BSG-1 h |
---|---|---|---|---|
• Healthy patients > 10 years of age • Prior to transplantation • Pregnancy scheduling • During pregnancy |
Glucose tolerance Glucose intolerance CFRD Indeterminate |
< 126 < 126 ≥ 126 < 126 |
< 140 140-199 ≥ 200 < 140 |
≥ 200 |
Monitorização de glicemia de jejum e GPP de 2 h | ||||
• During hospitalization • Outpatient setting 1. Pulmonary exacerbation, treated with i.v. antibiotic therapy or systemic glucocorticosteroids 2. Monthly, during and after nocturnal enteral feeding Glycated hemoglobin Random blood glucose testing |
DRFC DRFC DRFC |
GP de jejum ≥ 126 mg/dl GPP ≥ 200 mg/dl (persistente por 48 h) |
≥ 200 mg/dl durante ou após a dieta |
≥ 6,5% (< 6,5% não exclui) Glicemia ao acaso ≥ 200 mg/dl + poliúria e polidipsia |
OGTT: oral glucose tolerance test; BSG: blood serum glucose; BSG-2h: blood serum glucose 2 h after glucose intake during OGTT, GP-1h: blood serum glucose 2 h after glucose intake during OGTT; CFRD: cystic fibrosis-related diabetes; and PBG: postprandial blood glucose.
Adapted from Sermet-Gaudelus et al.(213)