Table 5. PPV and NPV of predicting HIV resistance for PR ARV drugs for both the ANRS algorithm alone and when the machine learning mutations are incorporated into them.

PPV: positive predictive value, NPV: negative predictive value, HIV: human immunodeficiency virus, PR: protease, AVR: antiretroviral, ANRS: National Agency for AIDS Research.

^aZ-score is >1.98, indicating there is a statically significant difference when adding the association matrix.