FIG. 8.

Electrically evoked auditory brainstem (EABR) amplitude growth function (AGF) results. Examples of EABR AGFs (EABR level versus stimulus level) are shown in the top-left panel. Slopes of EABR AGFs plotted as a function of SGN density for profiles A, B, and C for experimental, control, and comparison animals are shown in the top-right (SGN-A) and the two bottom panels (SGN-B and SGN-C). Symbols and colors follow the same rules as described for Figure 5 but the number of comparison cases for which EABR data were obtained is smaller. Slopes for individual cases represent mean slopes of multiple growth functions obtained during a period when slopes were relatively stable over time (day 150 post-implantation to sacrifice). The number of slopes per animal averaged 4.1 and the standard deviations averaged 3.8 μV/mA. The black regression lines and corresponding statistics show the relationship between EABR AGF slopes and SGN density for the AAV.Ntf3 group; black curving lines are 95 % confidence ranges.