Table 1.
Clinical Characteristics of Patient Cohort.
| Clinical Characteristics of the Patient Sample Set | |||||
|---|---|---|---|---|---|
| Characteristic | Total (N = 13) | EGFR Amplification (N = 5) | PTEN Loss (N = 10) | MGMT Methylation (N = 5) | IDH1 Mutation Positive (N = 3) |
| Histologic type and grade | |||||
| Grade III (AA) | 3 | 0 | 1 | 0 | 2 |
| Grade IV (GBM) | 10 | 5 | 9 | 5 | 1 |
| Age at diagnosis (yrs) | |||||
| Mean | 56.3 ± 14.6 | 65 ± 7.4 | 60.6 ± 12.2 | 66.8 ± 5.5 | 41 ± 19.1 |
| Range | 29–75 | 56–75 | 31–75 | 60–75 | 29–63 |
| Male sex | 5 | 2 | 4 | 2 | 2 |
| Female sex | 8 | 3 | 6 | 3 | 1 |
| Tumor location | |||||
| Frontal lobe | 2 | 2 | 2 | 1 | 0 |
| Parietal lobe | 4 | 1 | 3 | 1 | 1 |
| Temporal lobe | 7 | 2 | 5 | 3 | 2 |
| Laterality | |||||
| Left | 7 | 3 | 5 | 4 | 1 |
| Midline | 0 | 0 | 0 | 0 | 0 |
| Right | 6 | 2 | 5 | 1 | 2 |
Diagnostic and molecular characteristics of the patient cohort used for this study are displayed.