Figure 2.

Plasma exosome uptake by peripheral blood mononuclear cells. (A) Activation of cell subsets after incubated with plasma exosomes, with or without TCR activation; (B) Percentage of BODIPY TR positive cell subsets including CD14+ monocytes, CD20+ B cells, CD4+ and CD8+ T cells with exosome uptake, with or without TCR activation. PBMCs (1 × 10⁶) were incubated with BODIPY TR-labeled plasma exosomes (10⁸) for 24 hours in vitro in presence or absence of anti-CD3/CD28. Error bars represent means ± SE. ^*,#P < 0.05, compared with group without TCR-mediated activation.