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. 2017 Jul 25;40(12):1219–1229. doi: 10.1007/s40264-017-0574-6

Table 3.

Percentage frequency (positive cases/total cases examined) of abnormal objective findings in the patients examined

Group Hypotension Orthostatic intolerance Decreased skin temperature Flattened digital plethysmography Abnormality in cognitive function test Focal abnormality of CBF in SPECT
WAIS-III TMT
Diagnosed 72 cases (positive cases/total cases examined) 41.7 (30/72) 70.8 (34/48) (OH 17, POTS 17) 37.5 (21/56) 70.2 (40/57) 47.6 (10/21) 43.8 (7/16) 75.0 (12/16)
Definite 30 cases (positive cases/total cases examined) 46.7 (14/30) 83.3 (25/30) (OH 12, POTS 13) 62.1 (18/29) 86.2 (25/29) 58.3 (7/12) 50.0 (5/10) 88.9 (8/9)
Probable 42 cases (positive cases/total cases examined) 38.1 (16/42) 50.0 (9/18) (OH 5, POTS 4) 11.1 (3/27) 53.6 (15/28) 33.3 (3/9) 33.3 (2/6) 57.1 (4/7)
Undiagnosed 48 cases (positive cases/total cases examined) 29.2 (14/48) 50.0 (8/16) (OH 6, POTS 2) 28.0 (7/25) 36.0 (9/25) 25.0 (2/8) 14.3 (1/7) 50.0 (3/6)

CBF cerebral blood flow, OH orthostatic hypotension, POTS postural orthostatic tachycardia syndrome, SPECT single-photon emission computerized tomography, TMT Trail Making Test, WAIS-III Wechsler Intelligence Scale-Third Edition