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. 2017 Jun 21;65(6):553–564. doi: 10.1007/s00005-017-0479-1

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Comparison of dominant TCRs expressed by effector and regulatory CD4⁺ T cells in healthy and tumor-bearing TCRmini mice. The influence of the tumor on TCR repertoire of CD4⁺Teffs and Tregs. The frequencies of 35 most dominant TCRs from CD4⁺Teffs and Tregs from indicated sites of B16-Ep tumor-bearing (black bars) mice in comparison to TCRs present among circulating lymphocytes of healthy non-tumor-bearing control TCRmini mice (gray bars)