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. Author manuscript; available in PMC: 2017 Nov 16.
Published in final edited form as: Biomaterials. 2016 Mar 12;93:95–105. doi: 10.1016/j.biomaterials.2016.03.017

Figure 8. Conjugation to HyA reduces susceptibility to protease degradation by MMP-7.

Figure 8

A) 4-20% SDS-page gradient gel of sFlt and mvsFlt (650 kDa LCR) following 12 hour treatment with MMP-7 at high, medium and low molar ratios of MMP-7 to sFlt, which correspond to 1:1, 1:2 and 1:4 molar ratios of MMP-7 to sFlt. Band intensity was normalized to the no MMP-7 treatment within each group and background was subtracted from each sample using the blank well. B) Quantification of 4-20% gradient gel of sFlt and mvsFlt treated with MMP-7 at high, medium, and low molar ratios of sFlt to MMP-7 for 12 hours (*p<0.05; **p<0.01).