. 2017 Sep 12;13(11):5697–5708. doi: 10.1021/acs.jctc.7b00706

Table 1. Restrained Unbinding Free Energies, Standard-State Corrections, and Resulting Restrained Standard-State Binding Free Energies for wt UBM2 and P692A UBM2 Binding to UBI in Systems RS, ZS, and ZL, Respectively^a.

system	ΔG_unbind^res	ΔG_corr^⊖	ΔG_bind^⊖,res
RS/wt	27.0 ± 1.1	–9.2	–36.2 ± 1.1
ZS/wt	27.2 ± 2.8	–5.4	–32.6 ± 2.8
ZL/wt	30.1 ± 2.1	–5.4	–35.5 ± 2.1
RS/P692A	24.0 ± 0.6	–9.2	–33.2 ± 0.6
ZS/P692A	26.2 ± 1.8	–5.4	–31.6 ± 1.8
ZL/P692A	28.5 ± 1.9	–5.4	–33.9 ± 1.9

All free-energy values are in kJ·mol^–1.

Table 1. Restrained Unbinding Free Energies, Standard-State Corrections, and Resulting Restrained Standard-State Binding Free Energies for wt UBM2 and P692A UBM2 Binding to UBI in Systems RS, ZS, and ZL, Respectivelya.