Table 2.
Positional comparison | Model | bOdds Ratio | 95% Confidence Interval |
---|---|---|---|
rs12722 | |||
All athletes v Controls | CC/TT CC/Tcarriers Callele/Tallele |
1.70 1.45 1.28 |
1.19–2.42 1.07–1.97 1.08–1.52 |
RU athletes v Controls | CC/TT CC/Tcarriers Callele/Tallele |
1.76 1.53 1.30 |
1.22–2.54 1.11–2.09 1.09–1.55 |
Forwards v Controls | CC/TT CC/Tcarriers Callele/Tallele |
1.66 1.53 1.26 |
1.08–2.54 1.06–2.22 1.02–1.55 |
Backs v Controls | CC/TT CC/Tcarriers Callele/Tallele |
1.92 1.51 1.36 |
1.19–3.12 1.01–2.27 1.08–1.72 |
Back 3 and centres v Controls | CC/TT CC/Tcarriers Callele/Tallele |
2.30 1.76 1.48 |
1.29–4.08 1.09–2.78 1.12–1.96 |
rs3196378 | |||
All athletes v Controls | CC/AA CC/Acarriers Callele/Aallele |
1.83 1.66 1.32 |
1.29–2.59 1.22–2.25 1.12–1.56 |
RU athletes v Controls | CC/AA CC/Acarriers Callele/Aallele |
1.88 1.73 1.34 |
1.31–2.70 1.27–2.37 1.12–1.59 |
Forwards v Controls | CC/AA CC/Acarriers Callele/Aallele |
1.90 1.88 1.34 |
1.25–2.89 1.31–2.69 1.09–1.66 |
Backs v Controls | CC/AA CC/Acarriers Callele/Aallele |
1.85 1.54 1.33 |
1.14–2.99 1.02–2.31 1.06–1.68 |
Back 3 and centres v Controls | CC/AA CC/Acarriers Callele/Aallele |
2.25 1.78 1.46 |
1.27–4.00 1.11–2.84 1.11–1.93 |
Haplotypes and SNP epistasis | |||
All athletes v Controls | C–C/T–A aCC–CC |
1.31 1.97 |
1.10–1.56 1.44–2.69 |
RU athletes v Controls | C–C/T–A aCC–CC |
1.32 2.11 |
1.11–1.59 1.53–2.91 |
Forwards v Controls | C–C/T–A aCC–CC |
1.31 2.19 |
1.05–1.62 1.51–3.16 |
Backs v Controls | C–C/T–A aCC–CC |
1.36 1.86 |
1.07–1.72 1.29–2.67 |
Back 3 and centres v Controls | C–C/T–A aCC–CC |
1.49 2.35 |
1.12–1.99 1.47–3.77 |
aMDR best model versus all other genotype combinations for rs12722 and rs3196378
bAll odds ratios were statistically significant (P < 0.05)