Table 2.
Region | Seite | Mean ADC [μm2/s] | SD ADC [μm2/s] | Min ADC [μm2/s] | Max ADC [μm2/s] | ||||
---|---|---|---|---|---|---|---|---|---|
diseased | normal | diseased | normal | diseased | normal | diseased | normal | ||
Caudate nucleus | Right | 836.44a | 843.3 | 172.26 | 94.3 | 761.08 | 751.7 | 982.58 | 1089.5 |
Left | 906.5a | 962.4 | 187.08 | 103.2 | 827.13 | 864.4 | 1140.69 | 1125.0 | |
Thalamus | Right | 819.8 | 792.2 | 167.14 | 31.0 | 767.29 | 741.7 | 893.92 | 833.2 |
Left | 803.22 | 823.4 | 184.78 | 30.1 | 706.33 | 794.9 | 868.62 | 874.8 | |
Piriform lobec (incl. Amygdala) | Right | 958.96b | 895.0 | 184.23 | 50.6 | 856.72 | 806.0 | 1086.76 | 962.5 |
Left | 968.64b | 935.9 | 165.15 | 37.7 | 869.62 | 898.0 | 1049.03 | 1008.3 | |
Hippocampus | Right | 1027.93 | 1052.9 | 230.04 | 109.7 | 882.39 | 902.4 | 1230.62 | 1236.3 |
Left | 1002.14 | 1035.7 | 233.54 | 109.0 | 880.96 | 919.5 | 1138.59 | 1270.8 | |
Semioval center∆ | Right | 786.36 | 717.6 | 241.4 | 73.8 | 641.39 | 597.0 | 894.95 | 808.9 |
Left | 795.59 | 725.2 | 217.85 | 83.0 | 666.33 | 609.5 | 893.94 | 851.8 | |
Cerebral cortex | Right | 866.16 | 820.2 | 236.35 | 71.5 | 763.57 | 738.5 | 975.18 | 960.6 |
Left | 885.14 | 857.1 | 214.61 | 63.4 | 761.81 | 809.0 | 1055.38 | 962.6 |
Significant differences between the right and left cerebral hemisphere were found for the caudate nucleus (p < 0.0001) and the piriform lobe including the amygdala (p < 0.01). Significant differences between normal and diseased dogs were found for the piriform lobe including the amygdala and for the seminoval centre. Normal values are from the publication about normal dogs [32]
ADC apparent diffusion coefficient, Max maximum ADC, Min minimum ADC, SD standard deviation; a highly significant difference between right and left hemisphere <0.0001; bsignificant difference between right and left hemisphere p < 0.01; csignificant difference between normal and diseased dogs p = 0.02; ∆ significant difference between normal and diseased dogs p < 0.01