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Positive and negative factors differentially regulate AurA and Nek2. Positive regulators that stimulate depolymerization by AurA and Nek2 when cilia are disassembling are shown in green while factors that counteract depolymerization are shown in red. The downstream targets of the kinases, HDAC6 and KIF24 are shown in shades of purple. The letters X and Y indicated common but unknown negative and positive regulators. Negative regulation of AurA by Nek2 is indicated
